When a woman needs to confirm an oncological diagnosis or find out the reason for the absence of pregnancy during infertility treatment, the doctor prescribes certain diagnostic procedures. One of the most informative in this case is an endometrial biopsy. It allows you to examine the cells of the inner layer (mucous membrane) of the uterus under a microscope and detect even minimal pathological changes. Thanks to modern methods, such as punch biopsy, everything goes as quickly, safely and painlessly as possible.
Endometrial biopsy is a diagnostic procedure that involves taking a fragment of the uterine mucosa for further histological analysis. The procedure allows us to assess the structure of tissues, identify signs of inflammation, hyperplasia, polyps, adenomatosis, precancerous conditions or oncological processes.
An endometrial biopsy is prescribed when it is necessary to understand why the structure of the uterus is changed. The main indications for the procedure:
A timely procedure helps the doctor to accurately identify the problem, select an effective treatment and prevent complications.
The procedure is temporarily or not performed at all in such situations:
In each case, the decision to perform an endometrial biopsy is made by the doctor after an examination and tests. It is important to undergo preliminary diagnostics so that the procedure is as safe and effective as possible. And also find out the price of a pap biopsy in advance to plan treatment
In addition, endometrial pap biopsy does not require hospitalization and is painless.
A diagnostic curettage is a traditional method of obtaining endometrial tissue that involves the mechanical removal of the uterine mucosa using a curette. The procedure is performed under anesthesia, as it may require cervical dilation and is much more traumatic than modern methods. For a long time, curettage has been used for uterine bleeding, suspected endometrial hyperplasia, and as a preliminary step before some gynecological operations.
The technology of curettage has remained virtually unchanged for more than a century, which leads to its disadvantages: deeper trauma to the uterine walls, a higher risk of complications, uneven tissue sampling, and a longer recovery period. Because of this, the procedure has been gradually replaced in most cases by safe and informative methods, such as punch biopsy and hysteroscopic targeted sampling.
In modern practice, diagnostic curettage is not recommended for routine diagnosis. It remains advisable only in emergency situations, for example, in acute uterine bleeding, when it is necessary to quickly stop blood loss and obtain tissue for analysis.
Pipeline biopsy is a modern minimally invasive method of tissue sampling performed using a pipeline probe. It is a thin, flexible tube with a diameter of only 2-3 mm, inside which a vacuum is created for gentle aspiration of a microscopic amount of endometrium.
The procedure differs from other methods in the following ways:
When choosing a diagnostic method, it should be borne in mind that the price of an endometrial punch biopsy differs from the cost of a curettage, which is more expensive due to mandatory anesthesia. These manipulations are not the same procedure and have different pricing policies, although they are often used in combination. The total cost depends on the conditions of the procedure and the qualifications of the specialists in the chosen medical center.
The cost of diagnostic curettage and punch biopsy of the endometrium has significant differences due to the complexity of the manipulations. It is important to understand that curettage is a more expensive procedure because it requires mandatory anesthetic support and special operating room conditions. Instead, a pap biopsy is a less invasive method that often does not require anesthesia. These procedures are not identical: each has its own indications and can complement each other to establish an accurate diagnosis. The final price depends on the level of the clinic, the qualifications of the doctors, and the chosen examination method.
For the procedure to be comfortable and give the expected results, it is important to prepare for it properly:
Following these tips will make the procedure more predictable and comfortable for the patient. Also, the quality of the material obtained depends on the correct preparation, so it is part of a successful diagnosis.
The procedure is performed on an outpatient basis and does not require a long stay in the clinic.
If necessary, a repeat ultrasound is prescribed to assess the uterine cavity and its location relative to the cervix.
In general, the procedure takes no more than 5 minutes and is well tolerated by most women. The price of a pap biopsy of the endometrium at the IVMED fertility clinic in Kyiv is 1300 UAH. It should be noted that this price does not include sampling and histological examination of the material.
The most common question that worries women is whether endometrial pap biopsy has consequences. It is important to understand that this method of taking tissue from the uterine mucosa for examination is one of the safest gynecological procedures. Biopsy has no consequences for the reproductive system and fully preserves the ability to fertilize. It is atraumatic, i.e. it does not disrupt the structure of the endometrium. If performed correctly, there is no threat to a woman's health.
Complications are rare, but they are possible. Among them:
In most cases, patients tolerate the procedure well and recover quickly. However, it is recommended to discuss the price of endometrial biopsy and possible complications with your doctor during the consultation to have a complete understanding of the procedure.
Is endometrial biopsy painful?
Usually no. During the procedure, there may be only mild pulling sensations. The pipeline probe is very thin, so discomfort is minimal. This technique is considered the most comfortable among uterine biopsies.
How long will it take to get the results?
The histologic report is usually prepared within 14-21 days, depending on the workload of the laboratory.
Can I have a biopsy during my period?
No. After all, during menstruation, the endometrium is rejected, so the biomaterial is not suitable for analysis - the result will be unreliable.
Does the procedure affect the possibility of getting pregnant?
On the contrary. An endometrial biopsy is a key diagnostic step if a woman has been unable to get pregnant for a long time - the procedure helps to identify the causes of infertility. During such manipulations, the endometrium is not damaged, so there is no cause for concern.
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