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Cryopreservation of ovarian tissue

Modern reproductive medicine offers unique methods of preserving the possibility of conceiving a healthy child by effectively freezing germ cells, embryos, or even individual organs of the reproductive system, such as ovarian tissue.

What are the types of ovarian tissue cryopreservation?
1. Removal and cryofreezing of 50% of the ovarian body with the possibility of further transplantation on a vascular "leg" after the treatment of a concomitant disease (e.g. cancer). This technique is the most effective because it eliminates follicle loss due to tissue ischemia.

2. Multiple sampling and freezing of individual fragments of the ovary (cortical substance) with a size of about 5 mm cube. with the possibility of transplantation into a healthy ovary.

Indications for use

Increasingly, this technique is being offered to women undergoing long-term treatment for cancer, which imposes a certain risk of reproductive system dysfunction.

The main advantage of ovarian tissue cryopreservation is that if the treatment of the disease has led to infertility, the patient still has the opportunity to become pregnant with her own cells thanks to the preserved ovarian tissue.

 

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Advantages of the procedure

  • ovarian tissue for further cryopreservation can be obtained without delay, since there is no need for additional stimulation to obtain mature eggs
  • having a sexual partner is not necessary for a woman
  • a unique opportunity to preserve a large number of eggs in the follicles at the initial stage
  • no load on the hormonal system of the female body
  • There is no need to postpone the start of treatment (depending on the day of the cycle, etc.).

 

 

Preparation and course of the procedure

The IVMED clinic uses the Cryotissue vitrification system, which allows:

  • instantly freeze ovarian tissue at a speed of 23 thousand degrees per minute
  • eliminate the mechanism of formation of ice crystals that destroy cells
  • completely minimize the toxic effects of cryoprotectants on the tissue.

Vitrification is a method of rapid tissue freezing.

Features of the procedure

The main goal of ovarian tissue cryopreservation, its preservation, subsequent thawing, egg extraction from follicles and embryo cultivation is to preserve female fertility in patients with premature ovarian exhaustion syndrome or other diseases of the reproductive system.

1996 - the first procedure of cryopreservation of ovarian tissue was performed.

In 40% of women who have undergone chemotherapy, the reproductive system functions are restored after cryopreservation of ovarian tissue.

64% of women fully restore their reproductive function after cryopreservation.

Natural growth of follicles is observed after the effect of sex hormones on the woman's body after transplantation of thawed ovarian tissue

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Specialists of this service

Strelko
Galina Strelko
medical director, obstetrician-gynecologist of the highest category, Doctor of Medical Sciences
Work experience: more than 25 years
ulanova
Veranika Ulanova
Head of the medical and diagnostic department, obstetrician-gynecologist of the highest category
Work experience: more than 21 years
parpalej-1-1-min
Karolina Parpaley

obstetrician-gynecologist of the first category

Work experience: more than 16 years
макаренко
Liliia Makarenko

obstetrician-gynecologist of the highest category

Work experience: more than 14 years
пранова
Olga Pranova

obstetrician-gynecologist of the highest category

Work experience: more than 26 years
магера
Yulia Magera
obstetrician-gynecologist
Work experience: more than 6 years

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