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Treatment of male infertility

New medical technologies at the IVMED clinic effectively help in the most difficult cases of male infertility treatment.

IVMED Clinic is a..:

  • 7 types of semen tests in the andrology laboratory
  • 12 accurate methods for diagnosing the male factor of infertility
  • 5 effective methods of surgical sperm retrieval
  • 95% effectiveness of azoospermia treatment

Treatment of infertility in men

Approximately 30% of couples who are sexually active without contraceptives wait three months or more for a new addition to their family. Another 60% of couples wait more than seven months for a new addition. Only 10% of couples have a successful conception after almost a year of trying to conceive.

Doctors advise to see a reproductive specialist if a woman has no pregnancy after a year of active sexual activity. There are separate examination protocols for both partners.

Before the introduction of modern assisted reproductive technologies, it was mistakenly assumed that the reason for the absence of pregnancy lies in the woman’s condition. Today, according to statistics, about 40-45% of infertility cases are caused by male infertility. Therefore, reproductive specialists advise men to undergo an examination to determine the causes of infertility.

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Causes of male infertility in men

Male infertility can occur for a variety of reasons that affect the quantity and quality of sperm, their motility, or the process of sperm delivery. The main causes of male infertility include:

1

Anatomical abnormalities of the male genital organs (for example, hypospadias or obstruction of the vas deferens)

2

Sexual and ejaculatory dysfunction (impotence, retrograde ejaculation)

3

Endocrine hypothalamic-pituitary pathologies leading to disorders of spermatogenesis (hyperprolactinemia, hypogonadotropic hyponadism, etc.)

4

Inflammatory and infectious diseases (e.g., chronic prostatitis)

5

Disorders of spermatogenesis due to genetic diseases

6

Immunological disorders (the presence of autoimmune antibodies to sperm)

7

Disorders of spermatogenesis due to the influence of exogenous factors (radiation and chemotherapy, medication, alcohol, etc.)

8

Varicoceles

In cases where the cause of infertility cannot be established, the reproductive specialist diagnoses idiopathic infertility.

What are the signs of infertility in men?

A man’s reproductive potential is directly related to the quality and health of his sperm. Fertility is determined not only by quantitative indicators, but also by the functional characteristics of sperm. Normally, one milliliter of ejaculate contains from 60 to 120 million sperm. This production process is activated during puberty, when the body begins to produce approximately 1,000 sperm per second. However, various diseases or negative external factors can significantly disrupt spermatogenesis.

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The diagnosis of male infertility is made when a couple has regular unprotected sexual intercourse for 12 months without pregnancy, or when a man is diagnosed with pathologies that directly prevent conception. Timely detection of infertility is critical for reproductive medicine, as it allows specialists to immediately begin therapeutic measures aimed at restoring fertility and helping couples achieve the desired pregnancy.
However, some signs may indicate potential fertility problems:

Erection and ejaculation disorders

Pain or swelling in the testicular area

Problems with sexual function

Recurrent respiratory infections (may indicate abnormalities of sperm cilia)

Changes in ejaculate volume

Decreased sex drive

Anomalies in the development of the genitals

If any of these signs are present, a consultation with a reproductive medicine specialist is recommended to diagnose male infertility.

Types of male infertility

Male infertility is divided into several types depending on the causes and mechanisms of development:

Secretory (non-obstructive) infertility

impaired sperm formation in the testicles

Obstructive infertility

impaired patency of the urinary tract

Immunological infertility

the presence of antisperm antibodies

Idiopathic infertility

the causes are not established, despite a detailed examination

Absolute infertility

complete absence of sperm in the ejaculate (azoospermia)

Relative infertility

Reduced sperm count and quality (oligoasthenoteratozoospermia)

Symptoms of male infertility

As a rule, there are no symptoms of male infertility. A man learns about a low level of fertility at an appointment with an andrologist or reproductive specialist after the start of male infertility treatment and the necessary examinations.

There are several indirect factors of male infertility: a small amount of ejaculate, problems with potency, pain during intercourse.

Male infertility is increasingly associated with disorders of the formation and maturity of germ cells (gametes), i.e. their ability to fertilize an egg.

Methods of diagnosing infertility in men

A spermogram is a fundamental diagnostic tool in the study of male infertility, allowing for a comprehensive assessment of the qualitative and quantitative characteristics of ejaculate:

Sperm concentration:

the physiological range ranges from 15 to 200 million spermatozoa per milliliter of ejaculate, a significant deviation from these values may indicate a violation of spermatogenesis.

Morphological parameters:

A detailed analysis of the structural structure of spermatozoa, as deformities of the head, neck, or tail can significantly reduce fertilization capacity.

Physical activity:

determination of the percentage of progressively mobile, sedentary, and immobile spermatozoa, which directly affects their ability to reach the egg.

The volume of ejaculate:

Normal values are 1.5-5 ml, deviations in either direction may indicate pathological processes in the reproductive system.

In-depth diagnostics of male infertility includes:

Examination of the urethral secretion:

identification of infectious agents that negatively affect the quality of sperm and their fertilizing potential.

Hormonal profiling:

Comprehensive assessment of the functional state of the endocrine system, including levels of testosterone, follicle-stimulating and luteinizing hormones, prolactin and estradiol.

Ultrasound scanning of pelvic organs and scrotum:

detection of structural abnormalities, varicocele, tumors and other pathological changes in the reproductive organs.

Advanced ejaculate analytics:

includes an assessment of the degree of sperm maturity, their genetic material, and the level of oxidative stress affecting DNA integrity.

Chromosomal and genetic screening:

Identification of hereditary mutations, chromosomal aberrations, and immunological factors that may cause infertility.

Treatment of infertility in men

Approach to to the treatment of infertility in men depends on the identified causes and may include conservative or surgical methods, as well as the use of assisted reproductive technologies.

Conservative treatment of male infertility

Hormone therapy - prescription of drugs to normalize hormonal balance

Antibacterial therapy - treatment of infectious diseases of the genital organs

Antioxidant therapy - taking vitamins and minerals to improve sperm quality

Physiotherapy - methods of physical influence to improve blood circulation in the pelvic organs

Immunomodulatory therapy - for the treatment of immunological infertility

Conservative methods are most effective in the early stages of the disease and are often the first step in the treatment of male infertility.

Surgical treatment

Varicocelectomy - surgical treatment of varicose veins (dilated testicular veins)

Vasovasostomy - restoration of the patency of the vas deferens

Epididymovasostomy - surgical connection of the epididymis with the vas deferens

Removal of epididymal cysts

Surgical treatment of cryptorchidism (undescended testicles)

Innovative methods of treating male infertility

Microsurgical extraction of sperm from the testicle (MESA, TESE)

to obtain spermatozoa in case of azoospermia

Laser therapy

stimulation of spermatogenesis

Stem cells

experimental methods of restoring testicular function

Gene therapy

Correction of genetic defects affecting spermatogenesis

ICSI procedure for the treatment of male infertility

ICSI ( intracytoplasmic sperm injection) is one of the most effective methods of assisted reproductive technologies (ART) for the treatment of severe forms of male infertility at the IVMED clinic .

ICSI makes it possible to achieve fertilization even with a significant decrease in the number and quality of sperm, which makes this method indispensable in the treatment of severe forms of male infertility.

Our doctors

Олександр ОСТАПЧУК
Oleksandr Mykolayovych Ostapchuk
urologist, andrologist
Work experience: more than 10 years
Бенедичук Юрій Володимирович
Yuriy Benedychuk
obstetrician-gynecologist of the highest category, reproductive specialist, PhD
Work experience: more than 30 years

Licenses and certificates

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