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MAR test

is a method of immunological testing of biological material that helps to determine the presence of antisperm antibodies (i.e. antibodies to one's own germ cells) in the ejaculate, as well as their amounts.

MAR test is a standard test for determining the diagnosis of immunological infertility in men.

10% of all cases of infertility in a couple are associated with an immunological factor.

Antisperm antibodies are a class of complex proteins (immunoglobulins of the IgG, IgA or IgM types) that limit the speed and viability of a man's germ cells. When they are detected, an andrologist states the fact: the body perceives sperm as "foreign" and attacks them.

What is the essence of antisperm antibodies?
Antibodies are the human body's natural defense mechanism against foreign agents such as bacteria, cancer cells, or viruses. The cells of the immune system, with the help of special membranes on the membranes, are able to "recognize" these agents, triggering the mechanism of antibody formation. If, for some reason, the sperm membrane is also recognized by the body as "foreign", antibodies are formed to it by the same mechanism, the so-called antisperm antibodies.

Показання до проведення:

diagnosis of the male factor of infertility
the presence of diseases of the reproductive system in the history of a man
past surgical interventions on the reproductive system organs
determination of the sperm gluing factor in the spermogram
preparation for intrauterine insemination, in vitro fertilization protocol.

Переваги:

The reference values of the MAR test are the percentage of spermatozoa with antisperm antibodies.

more than 40% of sperm contain anti-sperm antibodies - gives reason to diagnose immunological infertility
from 0 to 40% of sperm contain anti-sperm antibodies - there is no immunological infertility

Preparation and/or course of the procedure

Simple recommendations that will allow you to get accurate and reliable results:

abstain from sexual intercourse and masturbation at least 3 days before the exam, but no more than 7 days before;
7 days before the biospecimen is submitted, refuse to drink all types of alcohol;
Quit smoking 3 hours before the biospecimen is submitted;
do not take hot baths, visit saunas or steam rooms 10 days before the delivery of the biomaterial;
If you take medications on a regular basis, especially if they include sedatives and antidepressants, please inform the IVMED clinic medical staff before you decide to take a spermogram. This is necessary to record this information in the study protocol.

Features and interesting facts

Masturbation is the ideal method for collecting a semen analysis.
It is not recommended to collect semen during interrupted sexual intercourse.
It is not recommended to collect semen from a used condom. Close contact with the latex material and lubricant in the condom can reduce the active functions of sperm and cause inaccurate diagnostic results.
It is recommended to keep the temperature in the range of 18 -25 C during all stages of sample collection and storage.
If the temperature changes or goes beyond the critical values, this will also affect the active functions of the sperm and cause inaccurate test results.
The World Health Organization and IVMED clinic specialists advise to donate sperm in the clinic so that diagnostics of the donated material can begin immediately after the ejaculate is donated.

Additional information:

One ejaculate sample can be used (with a sufficient volume) for all types of semen analysis at one time! That is, you can get the results of several tests at once.
For a comprehensive assessment of the male factor of infertility, we recommend obtaining the results of other ejaculate tests.
2 hours - this is how long it takes to get the results of the spermogram.

All procedures

Women:

Diseases:

Pregnancy management and preimplantation diagnostics

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