Today, reproductive medicine has made a huge step forward. Modern technologies make it possible to achieve pregnancy even in cases where natural fertilization seems impossible. One of these revolutionary achievements is the ICSI method. This is an assisted reproductive technology that helps to overcome even the most difficult cases of infertility and increases the chances of successful conception within the IVF program.
ICSI (Intracytoplasmic Sperm Injection) is an artificial insemination technique that involves the injection of a single, specially selected sperm directly into the cytoplasm of an egg using an ultra-thin glass needle under a microscope. This makes it possible to achieve pregnancy even in cases where there are very few sperm or they are inactive.
The ICSI procedure is carried out as part of an IVF cycle, but with the difference that conventional artificial insemination involves in vitro fertilization (in a test tube), where male gametes independently fertilize a female germ cell. But ICSI fertilization is performed manually by an embryologist. This technology becomes a real salvation for men with severe forms of infertility, because only one healthy sperm is enough for the procedure. This makes it possible to have a child even in cases where there are practically no viable cells in the ejaculate or sperm cannot overcome the protective membrane of the eggs due to low motility, morphological defects or other disorders.
Scientific research confirms that ICSI is a safe and effective method that minimizes the risk of genetic pathologies in the fetus and ensures a consistently high percentage of pregnancy. It guarantees the maximum use of the potential of each egg and is effective even when attempts at classical in vitro fertilization have failed.
The ICSI procedure in reproductive clinics may be recommended in the following cases:
Thus, the ICSI method is the optimal solution for couples where the male factor is the main cause of infertility. However, in recent years, ICSI has also been used in women of older reproductive age, when the quality of eggs deteriorates, ovulation is impaired, and the ovarian reserve is reduced. In addition, the technology can be prescribed in cases where problems with the permeability of the egg membrane have been identified (sperm cannot overcome the membrane on their own due to thickening or high density) or when a couple wants to minimize the risk of genetic abnormalities and use the highest quality germ cells.
Doctors may also recommend ICSI in the case of so-called "unexplained infertility" - when both partners have normal test results, but fertility treatment does not work and pregnancy does not occur. In such situations, micromanipulation technology allows you to bypass possible hidden fertilization problems that are difficult to detect using standard methods.
Also, this assisted reproductive technology allows couples to avoid using donor material in cases where it is possible to take at least one sperm from a man for fertilization. This allows preserving the genetic connection of the unborn child with both parents, which is an extremely important psychological aspect for many families.
ICSI IVF has many advantages that make this method the most promising among other assisted reproductive technology programs:
Another advantage is the possibility of using frozen sperm or eggs without reducing the chances of success. This opens up additional prospects for couples who plan to postpone pregnancy or are undergoing treatment that is incompatible with conception.
Thanks to this, the use of ICSI gives consistently high pregnancy rates even in patients who have not been able to get pregnant for a long time.
In our ICSI clinic, the procedure is performed in several successive stages, each of which is important for the final result. IVMED doctors always follow international protocols, thereby guaranteeing the safety and effectiveness of the method. Each couple receives a personal coordinator who accompanies patients at all stages of the program. This approach helps to avoid stress and also ensures transparency of the process, because the couple understands what is happening at every step.
Before starting the program, a reproductive specialist consults with the patient and performs a complete diagnosis: semen analysis, hormonal tests, ultrasound, etc. Particular attention is paid to the quality of the ejaculate. Based on the results, the doctor draws up an individual treatment plan.
In addition, both partners are screened for sexually transmitted infections and tested for compatibility. This helps to avoid complications and guarantees the best conditions for the future embryo.
A woman may be prescribed ovulation stimulation to obtain a higher number of mature eggs than during the natural ovulation cycle. For this purpose, modern protocols are used that minimize the hormonal load on the woman's body but allow for high-quality eggs. During this period, it is important to follow the doctor's recommendations regarding nutrition, physical activity, vitamin intake, and avoid stress.
After the stimulation, when the follicles reach the desired size, an ovarian puncture is performed, a minimally invasive procedure during which eggs are taken from the follicles. The procedure lasts about 15-20 minutes and is performed under short-term anesthesia. The obtained eggs are transferred to the laboratory, where they are evaluated according to their maturity.
The embryologist analyzes the sperm sample under a microscope and selects the highest quality sperm with the correct morphology - motile, with the perfect head and tail shape. It will become a "candidate" for fertilization. If spermatozoa were obtained by the PESA TESA or TESE method (sampling from the testicle or its epididymis), special preparation is performed - the material is cleaned of plasma and non-viable cells, selecting the best gamete from them.
This is the most crucial stage of IVF with ICSI. Using a microneedle, the embryologist injects the sperm directly into the egg. The process takes place with micron precision and is monitored under a microscope with multiple magnification, so the possibility of error is excluded.
After fertilization, the eggs are transferred to special incubators, where conditions are created that are as close as possible to the natural fallopian tubes. There they develop for five days. Embryologists closely monitor the development of embryos, choosing the most promising ones for embryo transfer.
One or more of the highest quality embryos are transferred into the woman's uterine cavity. The procedure is painless and does not require anesthesia. After that, the most important stage begins - waiting for the implantation of the embryo. The patient is provided with full informational support, prescribed appropriate therapy and monitored until the pregnancy is confirmed. The test is performed 2 weeks after the embryo transfer.
The cost of the procedure depends on various factors: the complexity of the case, the number of necessary examinations, the condition of the sperm and eggs, the need to use donor material or additional procedures (preimplantation genetic testing, cryopreservation, multiple embryo transfer).
At the IVMED clinic, the price starts at about UAH 50,000. However, the exact cost of ICSI can be found out after consultation with a doctor, since each program is made individually. Specialists help you choose the best option, taking into account all the medical and financial capabilities of patients. Couples also receive detailed information about the stages of the program and a forecast of the results.
The effectiveness of the method depends on many factors, such as the woman's age, the quality of eggs and sperm, the condition of the endometrium, etc. However, ICSI IVF demonstrates one of the highest success rates among all reproductive technologies - up to 95% of fertilized eggs form viable embryos.
The high efficiency of the method is explained:
Testimonials from patients who have undergone ICSI speak for themselves: after years of unsuccessful attempts to get pregnant, this procedure has become a decisive step on the way to having a child. According to international studies, more than 70% of women become pregnant after the first or second attempt. But an important success factor is not only the technical perfection of the method, but also the proper preparation of the woman's body.
The IVMED fertility clinic in Kyiv is one of the leading reproductive medicine centers in Ukraine, which uses advanced technologies, high-precision equipment, and personalized programs for each patient. The clinic adheres to international standards and protocols, and implements programs with genetic diagnosis of embryos. This helps prevent hereditary diseases and ensure the birth of a healthy child.
A modern laboratory, comfortable conditions and professional support create the most favorable environment for achieving the desired result. Each stage is performed under the supervision of several specialists, which eliminates the risk of errors. And the use of the latest equipment allows us to work at the cellular level with maximum accuracy.
It's worth noting that the process of infertility treatment is often associated with a great deal of emotional stress. That is why patients at the center can count on psychological support to help them overcome anxiety and tune in to a positive outcome.
When patients come to IVMED for ICSI, they receive not just a medical service, but a team that accompanies them step by step to the main goal of life - the birth of a desired, healthy child.
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